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Journal article

Association between single nucleotide polymorphism-genotype and outcome of patients with chronic lymphocytic leukemia in a randomized chemotherapy trial.

Abstract:

BACKGROUND: There is variability in the outcome of patients with chronic lymphocytic leukemia with apparently the same stage of disease. Identifying genetic variants that influence patients' outcome and response to treatment may provide important insights into the biology of the disease. DESIGN AND METHODS: We investigated the possibility that genetic variation influences outcome by conducting a genome-wide analysis of 346,831 single nucleotide polymorphisms in 356 patients entered into a pha...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit
Role:
Author
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Journal:
Haematologica
Volume:
96
Issue:
10
Pages:
1496-1503
Publication date:
2011-10-05
DOI:
EISSN:
1592-8721
ISSN:
0390-6078
URN:
uuid:ed76fefc-c6fa-4565-9012-1e37ee8eddf5
Source identifiers:
192950
Local pid:
pubs:192950

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