Journal article
Gene loops juxtapose promoters and terminators in yeast.
- Abstract:
-
Mechanistic analysis of transcriptional initiation and termination by RNA polymerase II (PolII) indicates that some factors are common to both processes. Here we show that two long genes of Saccharomyces cerevisiae, FMP27 and SEN1, exist in a looped conformation, effectively bringing together their promoter and terminator regions. We also show that PolII is located at both ends of FMP27 when this gene is transcribed from a GAL1 promoter under induced and noninduced conditions. Under these con...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1038/ng1411
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Authors
Bibliographic Details
- Publisher:
- Nature Publishing Group Publisher's website
- Journal:
- Nature Genetics Journal website
- Volume:
- 36
- Issue:
- 9
- Pages:
- 1014-1018
- Publication date:
- 2004-01-01
- Acceptance date:
- 2004-07-14
- DOI:
- EISSN:
-
1546-1718
- ISSN:
-
1061-4036
- Source identifiers:
-
15846
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:15846
- UUID:
-
uuid:ed6e1512-fef0-4532-808b-b3529730e8f1
- Local pid:
- pubs:15846
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Nature Publishing Group
- Copyright date:
- 2004
- Notes:
- Copyright © 2004 Nature Publishing Group.
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