- Abstract:
-
Mechanistic analysis of transcriptional initiation and termination by RNA polymerase II (PolII) indicates that some factors are common to both processes. Here we show that two long genes of Saccharomyces cerevisiae, FMP27 and SEN1, exist in a looped conformation, effectively bringing together their promoter and terminator regions. We also show that PolII is located at both ends of FMP27 when this gene is transcribed from a GAL1 promoter under induced and noninduced conditions. Under these con...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Publisher copy:
- 10.1038/ng1411
-
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- Publisher:
- Nature Publishing Group Publisher's website
- Journal:
- Nature Genetics Journal website
- Volume:
- 36
- Issue:
- 9
- Pages:
- 1014-1018
- Publication date:
- 2004-01-01
- DOI:
- EISSN:
-
1546-1718
- ISSN:
-
1061-4036
- URN:
-
uuid:ed6e1512-fef0-4532-808b-b3529730e8f1
- Source identifiers:
-
15846
- Local pid:
- pubs:15846
- Language:
- English
- Keywords:
- Copyright holder:
- Nature Publishing Group
- Copyright date:
- 2004
- Notes:
- Copyright © 2004 Nature Publishing Group.
Journal article
Gene loops juxtapose promoters and terminators in yeast.
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