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Journal article

Multiple sclerosis, vitamin D, and HLA-DRB1*15.

Abstract:

BACKGROUND: Multiple sclerosis (MS) has a remarkable geographic distribution inversely paralleling that of regional ultraviolet radiation, supporting the hypothesis that vitamin D plays a central role in the disease etiology. The major histocompatibility complex exerts the largest genetic contribution to MS susceptibility, but much risk remains unexplained and direct gene-environment interaction is a strong candidate for this additional risk. Such interactions may hold the key for disease pr...

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Publication status:
Published

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Authors


Handunnetthi, L More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, WTC Human Genetics
Journal:
Neurology
Volume:
74
Issue:
23
Pages:
1905-1910
Publication date:
2010-06-05
DOI:
EISSN:
1526-632X
ISSN:
0028-3878
URN:
uuid:ed4fb13c-1143-4698-aacc-e82a3d175c83
Source identifiers:
60446
Local pid:
pubs:60446

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