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Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes.

Abstract:

BACKGROUND: In patients with type 2 diabetes, the effects of intensive glucose control on vascular outcomes remain uncertain. METHODS: We randomly assigned 11,140 patients with type 2 diabetes to undergo either standard glucose control or intensive glucose control, defined as the use of gliclazide (modified release) plus other drugs as required to achieve a glycated hemoglobin value of 6.5% or less. Primary end points were composites of major macrovascular events (death from cardiovascular c...

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Publication status:
Published

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Publisher copy:
10.1056/NEJMoa0802987

Authors


MacMahon, S More by this author
Chalmers, J More by this author
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Journal:
The New England journal of medicine
Volume:
358
Issue:
24
Pages:
2560-2572
Publication date:
2008-06-06
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
URN:
uuid:ed493b4f-4199-4d25-a379-30326481b1ae
Source identifiers:
215645
Local pid:
pubs:215645

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