Multiple newly identified loci associated with prostate cancer susceptibility.

Journal article

Prostate cancer is the most common cancer affecting males in developed countries. It shows consistent evidence of familial aggregation, but the causes of this aggregation are mostly unknown. To identify common alleles associated with prostate cancer risk, we conducted a genome-wide association study (GWAS) using blood DNA samples from 1,854 individuals with clinically detected prostate cancer diagnosed at

Authors: Eeles, R; Kote-Jarai, Z; Giles, G; Olama, A; Guy, M

• Publication status: Published
• Journal: Nature genetics
• Volume: 40
• Issue: 3
• Pages: 316-321
• Publication date: 2008-03-01
• DOI: 10.1038/ng.90
• EISSN: 1546-1718
• ISSN: 1061-4036
• Language: English
• Keywords: Quantitative Trait Loci; British Association of Urological Surgeons' Section of Oncology; Polymorphism, Single Nucleotide; Male; Adult; Aged; Great Britain; Aged, 80 and over; UK Genetic Prostate Cancer Study Collaborators; Genetic Predisposition to Disease; Genotype; Chromosome Mapping; Middle Aged; Australia; UK ProtecT Study Collaborators; Prostatic Neoplasms; Algorithms; Humans; Case-Control Studies