Hughes abdominal closure versus standard mass closure to reduce incisional hernias following surgery for colorectal cancer: the HART RCT

Journal article

BackgroundIncisional hernias can cause chronic pain and complications and affect quality of life. Surgical repair requires health-care resources and has a significant associated failure rate. A prospective, multicentre, single-blinded randomised controlled trial was conducted to investigate the clinical effectiveness and cost-effectiveness of the Hughes abdominal closure method compared with standard mass closure following surgery for colorectal cancer. The study randomised, in a 1 : 1 ratio,...

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Authors: O'Connell, S; Islam, S; Sewell, B; Farr, A; Knight, L

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: NIHR Journals Library
• Journal: Health Technology Assessment
• Volume: 26
• Issue: 34
• Pages: 1-100
• Publication date: 2022-08-01
• DOI: 10.3310/cmwc8368
• EISSN: 2046-4924
• ISSN: 1366-5278
• Language: English
• Keywords: Medicine; Confidence interval; Colorectal cancer; Internal medicine; Surgery; Hernia; Incisional hernia; Cancer; Odds ratio; Quality of life (healthcare); Randomized controlled trial; Nursing; Incidence (geometry)