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SSRI treatment decreases prolactin and hyperthermic responses to mCPP.

Abstract:

We studied the effect of 3 weeks treatment with the selective serotonin re-uptake inhibitor (SSRI), paroxetine (30 mg daily), on the neuroendocrine and hyperthermic responses to the 5-HT2C receptor agonist, m-chlorophenylpiperazine (mCPP) (0.05 mg/kg i.v.), in seven healthy volunteers. Following paroxetine treatment, both the prolactin and hyperthermic responses to mCPP were significantly attenuated. These data are consistent with experimental animal studies indicating that repeated SSRI trea...

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Publication status:
Published

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Publisher copy:
10.1007/s002130050406

Authors


Quested, DJ More by this author
Sargent, PA More by this author
Journal:
Psychopharmacology
Volume:
133
Issue:
3
Pages:
305-308
Publication date:
1997-10-05
DOI:
EISSN:
1432-2072
ISSN:
0033-3158
URN:
uuid:ed2cdc58-ddca-4f83-b2b9-4724e719eb8a
Source identifiers:
186048
Local pid:
pubs:186048

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