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Triazine probes targeting ascorbate peroxidases in plants

Abstract:

Though they are rare in nature, anthropogenic 1,3,5-triazines have been used in herbicides as chemically stable scaffolds. Here, we show that small 1,3,5-triazines selectively target ascorbate peroxidases (APXs) in Arabidopsis (Arabidopsis thaliana), tomato (Solanum lycopersicum), rice (Oryza sativa), maize (Zea mays), liverwort (Marchantia polymorpha), and other plant species. The alkyne-tagged 2-chloro-4-methyl-1,3,5-triazine probe KSC-3 selectively binds APX enzymes, both in crude extracts...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1104/pp.19.00481

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Plant Sciences
Role:
Author
Publisher:
American Society of Plant Biologists
Journal:
Plant Physiology More from this journal
Volume:
180
Issue:
4
Pages:
1848-1859
Publication date:
2019-05-28
Acceptance date:
2019-05-06
DOI:
EISSN:
1532-2548
ISSN:
0032-0889
Pmid:
31138623
Language:
English
Pubs id:
pubs:1004817
UUID:
uuid:ed22c3db-7b4b-4b9c-9d4c-4ba3a67a8a71
Local pid:
pubs:1004817
Source identifiers:
1004817
Deposit date:
2019-06-26

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