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Cascade palladium-catalyzed alkenyl aminocarbonylation/ intramolecular aryl amidation: an annulative synthesis of 2-quinolones.

Abstract:
Palladium-catalyzed intermolecular aminocarbonylation/intramolecular amidation cascade sequences can be used to convert a range of 2-(2-haloalkenyl)aryl halide substrates efficiently and selectively to the corresponding 2-quinolones. Delaying the introduction of the CO atmosphere allows an amination/carbonylation sequence and the preparation of an isoquinolone.
Publication status:
Published

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Publisher copy:
10.1021/ol802624e
Journal:
Organic letters More from this journal
Volume:
11
Issue:
3
Pages:
583-586
Publication date:
2009-02-01
DOI:
EISSN:
1523-7052
ISSN:
1523-7060
Language:
English
Keywords:
Pubs id:
pubs:52479
UUID:
uuid:ed0be9ef-dffb-4ed6-a9c6-69b086b670eb
Local pid:
pubs:52479
Source identifiers:
52479
Deposit date:
2012-12-19

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