Reversibility of retinal microvascular changes in severe falciparum malaria.

Journal article

Malarial retinopathy allows detailed study of central nervous system vascular pathology in living patients with severe malaria. An adult with cerebral malaria is described who had prominent retinal whitening with corresponding retinal microvascular obstruction, vessel dilatation, increased vascular tortuosity, and blood retinal barrier leakage with decreased visual acuity, all of which resolved on recovery. Additional study of these features and their potential role in elucidating the pathogenesis of cerebral malaria is warranted.

Authors: Maude, R; Kingston, H; Joshi, S; Mohanty, S; Mishra, S

• Publication status: Published
• Publisher: American Society of Tropical Medicine and Hygiene
• Journal: American journal of tropical medicine and hygiene
• Volume: 91
• Issue: 3
• Pages: 493-495
• Publication date: 2014-09-01
• DOI: 10.4269/ajtmh.14-0116
• EISSN: 1476-1645
• ISSN: 0002-9637
• Language: English
• Keywords: Humans; India; Eye Infections, Parasitic; Retinal Vessels; Male; Retina; Retinal Diseases; Malaria, Cerebral; Young Adult; Malaria, Falciparum