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Venom phospholipases of Russell's vipers from Myanmar and eastern India--cloning, characterization and phylogeographic analysis.

Abstract:

Venoms of Russell's vipers (genus Daboia) are known for their deadly coagulopathic and other effects. We herein studied various isoforms of venom phospholipases A(2) (PLAs) from two Daboia species at their geographic boundary. From Myanmar Daboia siamensis venom (designated as DsM), four PLAs (designated DsM-aI, aI', aII' and bI') were purified, and the cDNAs encoding two acidic (DsM-aI and aII) and two basic PLAs (DsM-bI and S1) were also cloned from its venom-glands. DsM-S1 is identical to ...

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Publication status:
Published

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Authors


Warrell, DA More by this author
Journal:
Biochimica et biophysica acta
Volume:
1774
Issue:
8
Pages:
1020-1028
Publication date:
2007-08-05
DOI:
ISSN:
0006-3002
URN:
uuid:ecedd501-ddd7-44b3-b506-aae565ca2f11
Source identifiers:
61037
Local pid:
pubs:61037

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