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The impact of IPTi and IPTc interventions on malaria clinical burden - in silico perspectives.

Abstract:

BACKGROUND: Clinical management of malaria is a major health issue in sub-Saharan Africa. New strategies based on intermittent preventive treatment (IPT) can tackle disease burden by simultaneously reducing frequency of infections and life-threatening illness in infants (IPTi) and children (IPTc), while allowing for immunity to build up. However, concerns as to whether immunity develops efficiently in treated individuals, and whether there is a rebound effect after treatment is halted, have ...

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Publication status:
Published

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Authors


Lourenço, JM More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Journal:
PloS one
Volume:
4
Issue:
8
Pages:
e6627
Publication date:
2009
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
URN:
uuid:eceb2d94-3400-4432-a4a7-3ea47291de53
Source identifiers:
134557
Local pid:
pubs:134557

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