Journal article icon

Journal article

In vivo biodistribution and efficacy of peptide mediated delivery.

Abstract:

To transverse the plasma membrane and gain access to the cellular interior is one of the major obstacles for many novel pharmaceutical molecules. Since the late 1990s, cell-penetrating peptides (CPPs) have been utilized as transport vectors for a broad spectrum of 'biological cargoes', ranging from inert gold particles to multifaceted macromolecules such as proteins and plasmids. Numerous studies have shown that CPPs are efficient carriers for bioactive cargoes in vitro. However, even though ...

Expand abstract

Actions


Access Document


Publisher copy:
10.1016/j.tips.2010.07.006

Authors


Järver, P More by this author
Langel, Ü More by this author
Journal:
Trends in pharmacological sciences
Volume:
31
Issue:
11
Pages:
528-535
Publication date:
2010-11-05
DOI:
EISSN:
1873-3735
ISSN:
0165-6147
URN:
uuid:ecd8ed91-c041-4048-88bc-6b0e34a5d8e0
Source identifiers:
354333
Local pid:
pubs:354333

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP