Journal article
Progressive 3q amplification consistently targets SOX2 in preinvasive squamous lung cancer.
- Abstract:
-
RATIONALE: Amplification of distal 3q is the most common genomic aberration in squamous lung cancer (SQC). SQC develops in a multistage progression from normal bronchial epithelium through dysplasia to invasive disease. Identifying the key driver events in the early pathogenesis of SQC will facilitate the search for predictive molecular biomarkers and the identification of novel molecular targets for chemoprevention and therapeutic strategies. For technical reasons, previous attempts to analy...
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- Publisher copy:
- 10.1164/rccm.201001-0005oc
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Authors
Bibliographic Details
- Journal:
- American journal of respiratory and critical care medicine
- Volume:
- 182
- Issue:
- 1
- Pages:
- 83-91
- Publication date:
- 2010-07-01
- DOI:
- EISSN:
-
1535-4970
- ISSN:
-
1073-449X
- Source identifiers:
-
324308
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:324308
- UUID:
-
uuid:ecc2e148-37f6-42e1-86d7-10fd5b8bdadf
- Local pid:
- pubs:324308
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2010
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