Journal article
Selective labelling of the hydrophobic segments of intrinsic membrane proteins with a lipophilic photogenerated carbene.
- Abstract:
-
HYDROPHOBIC photogenerated reagents are attractive candidates for the labelling of those parts of membrane proteins that are buried within the lipid bilayer. Recently, nitrenes generated from aryl azides have been used to distinguish intrinsic from extrinsic membrane proteins1-4 and to label glycophorin A in or close to the transmembrane hydrophobic sequence 5. We have questioned the use of aryl nitrenes on the basis of their evident lack of reactivity towards carbon-hydrogen bonds in single-...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Nature More from this journal
- Volume:
- 280
- Issue:
- 5725
- Pages:
- 841-843
- Publication date:
- 1979-08-01
- DOI:
- EISSN:
-
1476-4687
- ISSN:
-
0028-0836
Item Description
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:52422
- UUID:
-
uuid:ecb897da-a75a-44eb-b480-435d4dca837e
- Local pid:
-
pubs:52422
- Source identifiers:
-
52422
- Deposit date:
-
2012-12-19
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- Copyright date:
- 1979
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