A simplified, low-cost method for polarized light microscopy.

Journal article

Abstract:: Malaria pigment is an intracellular inclusion body that appears in blood and tissue specimens on microscopic examination and can help in establishing the diagnosis of malaria. In simple light microscopy, it can be difficult to discern from cellular background and artifacts. It has long been known that if polarized light microscopy is used, malaria pigment can be much easier to distinguish. However, this technique is rarely used because of the need for a relatively costly polarization microscope. We describe a simple and economical technique to convert any standard light microscope suitable for examination of malaria films into a polarization microscope.

Journal:: American journal of tropical medicine and hygiene More from this journal
Volume:: 81
Issue:: 5
Pages:: 782-783
Publication date:: 2009-11-01
DOI:: 10.4269/ajtmh.2009.09-0383
EISSN:: 1476-1645
ISSN:: 0002-9637

Language:: English
Keywords:: Hemeproteins

Erythrocytes

Plasmodium falciparum

Humans

Malaria, Falciparum

Microscopy, Polarization

Animals
Pubs id:: pubs:133613
UUID:: uuid:ecb7deac-83fd-444d-af06-b0d7cfdce5a0
Local pid:: pubs:133613
Source identifiers:: 133613
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_ecb7deac83fd444daf06b0d7cfdce5a0

Licence:: Terms and Conditions of Use for Oxford University Research Archive

If you are the owner of this record, you can report an update to it here: Report update to this record