- Abstract:
-
Background
Chronic hepatitis C (CHC) is associated with systemic insulin resistance, yet there are limited data on the tissue‐specific contribution in vivo to this adverse metabolic phenotype, and the effect of HCV cure.Methods
We examined tissue‐specific insulin sensitivity in a cohort study involving 13 patients with CHC compared to 12 BMI‐matched healthy control subjects. All subjects underwent a two‐step clamp incorporating the use of stable isotopes to measure car... Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 612.3KB)
-
- Publisher copy:
- 10.1111/cen.13924
-
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- Publisher:
- Wiley Publisher's website
- Journal:
- Clinical Endocrinology Journal website
- Volume:
- 90
- Issue:
- 3
- Pages:
- 440-448
- Publication date:
- 2018-12-26
- Acceptance date:
- 2018-12-20
- DOI:
- EISSN:
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1365-2265
- ISSN:
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0300-0664
- Pubs id:
-
pubs:955037
- URN:
-
uri:ecb5c76e-31fa-41bf-a6ca-b43ebb8afdec
- UUID:
-
uuid:ecb5c76e-31fa-41bf-a6ca-b43ebb8afdec
- Local pid:
- pubs:955037
- Language:
- English
- Keywords:
- Copyright holder:
- Lim et al
- Copyright date:
- 2018
- Notes:
-
© 2018 The Authors. Clinical Endocrinology Published by John Wiley and Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Journal article
Hepatitis C virus infection is associated with hepatic and adipose tissue insulin resistance that improves after viral cure
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