Journal article icon

Journal article

Cytotoxic T lymphocytes recognize influenza haemagglutinin that lacks a signal sequence

Abstract:

A surprising feature of most cytotoxic T lymphocytes (CTL) responding to influenza infection is that they recognize the unglycosylated (non-transmembrane) proteins of the virus, including the nucleoprotein. Recognition of cells that express nucleoprotein by CTL does not depend on a definite signal sequence within the protein, and the epitopes recognized can be defined with short synthetic peptides in vitro. Haemagglutinin (HA), the major transmembrane protein of the virus, is recognized by a ...

Expand abstract

Actions


Journal:
Nature More from this journal
Volume:
324
Issue:
6097
Pages:
575-577
Publication date:
1986-01-01
ISSN:
0028-0836
Language:
English
Pubs id:
pubs:95056
UUID:
uuid:ec927428-2744-4dfc-bd44-29b9ec0152ab
Local pid:
pubs:95056
Source identifiers:
95056
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP