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Journal article

Atherosclerotic lesions in genetically modified mice quantified in vivo by non-invasive high-resolution magnetic resonance microscopy.

Abstract:

We have previously shown that magnetic resonance microscopy (MRM) accurately quantifies atherosclerosis in Apolipoprotein E deficient (ApoE(-/-)) mice aged 36-84 weeks. The present study tests MRM in the quantification of aortic atherosclerosis over a broader range of lesion severity. Younger mice with less advanced disease were imaged in order to evaluate sensitivity, specificity and maximum practical resolution of MRM. Nineteen mice underwent in vivo MRM. Wall area measurements by MRM and l...

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Publication status:
Published

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Authors


Choudhury, RP More by this author
Aguinaldo, JG More by this author
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Journal:
Atherosclerosis
Volume:
162
Issue:
2
Pages:
315-321
Publication date:
2002-06-05
DOI:
EISSN:
1879-1484
ISSN:
0021-9150
URN:
uuid:ec5eba96-8c96-4b45-9386-051694f5e725
Source identifiers:
163147
Local pid:
pubs:163147

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