Journal article
Rewritable glycochips.
- Abstract:
- We describe microarraying of carbohydrates for protein screening using either disulfide bridge or Schiff base imine immobilization chemistries on plasmachemical deposited functional nanolayers. The commonly observed issue of nonspecific background binding of proteins is overcome by spotting carbohydrates through a protein-resistant overlayer yielding spatially localized interaction with a reactive functional underlayer.
- Publication status:
- Published
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- Publisher copy:
- 10.1021/ja901294r
Authors
- Journal:
- Journal of the American Chemical Society More from this journal
- Volume:
- 131
- Issue:
- 22
- Pages:
- 7755-7761
- Publication date:
- 2009-06-01
- DOI:
- EISSN:
-
1520-5126
- ISSN:
-
0002-7863
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:41246
- UUID:
-
uuid:ec5c3681-deb6-4ad8-a799-6c329eed71c9
- Local pid:
-
pubs:41246
- Source identifiers:
-
41246
- Deposit date:
-
2012-12-19
- ARK identifier:
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- Copyright date:
- 2009
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