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Journal article

Rewritable glycochips.

Abstract:
We describe microarraying of carbohydrates for protein screening using either disulfide bridge or Schiff base imine immobilization chemistries on plasmachemical deposited functional nanolayers. The commonly observed issue of nonspecific background binding of proteins is overcome by spotting carbohydrates through a protein-resistant overlayer yielding spatially localized interaction with a reactive functional underlayer.
Publication status:
Published

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Publisher copy:
10.1021/ja901294r

Authors

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author


Journal:
Journal of the American Chemical Society More from this journal
Volume:
131
Issue:
22
Pages:
7755-7761
Publication date:
2009-06-01
DOI:
EISSN:
1520-5126
ISSN:
0002-7863


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