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Isogenic autosomes to be applied in optimal screening for novel mutants with viable phenotypes in Drosophila melanogaster.

Abstract:

Most insertional mutagenesis screens of Drosophila performed to date have not used target chromosomes that have been checked for their suitability for phenotypic screens for viable phenotypes. To address this, we have generated a selection of stocks carrying either isogenized second chromosomes or isogenized third chromosomes, in a genetic background derived from a Canton-S wild-type strain. We have tested these stocks for a range of behavioral and other viable phenotypes. As expected, most l...

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Publisher copy:
10.1080/01677060591007155

Authors


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Journal:
Journal of neurogenetics
Volume:
19
Issue:
2
Pages:
57-85
Publication date:
2005-01-01
DOI:
EISSN:
1563-5260
ISSN:
0167-7063
URN:
uuid:ec522931-d6e2-4fd4-90b4-3e593a970a8f
Source identifiers:
315606
Local pid:
pubs:315606

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