Spatio-temporal epidemiology of Campylobacter jejuni enteritis, in an area of Northwest England, 2000-2002.

Journal article

A total of 969 isolates of Campylobacter jejuni originating in the Preston, Lancashire postcode district over a 3-year period were characterized using multi-locus sequence typing. Recently developed statistical methods and a genetic model were used to investigate temporal, spatial, spatio-temporal and genetic variation in human C. jejuni infections. The analysis of the data showed statistically significant seasonal variation, spatial clustering, small-scale spatio-temporal clustering and spatio-temporal interaction in the overall pattern of incidence, and spatial segregation in cases classified according to their most likely species-of-origin.

Authors: Gabriel, E; Wilson, D; Leatherbarrow, A; Cheesbrough, J; Gee, S

• Publication status: Published
• Journal: Epidemiology and infection
• Volume: 138
• Issue: 10
• Pages: 1384-1390
• Publication date: 2010-10-01
• DOI: 10.1017/s0950268810000488
• EISSN: 1469-4409
• ISSN: 0950-2688
• Language: English
• Keywords: Humans; Aged, 80 and over; Child, Preschool; Child; Young Adult; Male; Molecular Epidemiology; Sequence Analysis, DNA; Aged; Campylobacter Infections; Time Factors; Female; England; Middle Aged; Infant, Newborn; Enteritis; Seasons; Infant; DNA Fingerprinting; Campylobacter jejuni; Bacterial Typing Techniques; Foodborne Diseases; Genotype; Adolescent; DNA, Bacterial; Adult; Cluster Analysis