Brain opiates and neuroendocrine function.

Journal article

Opioid peptides are found throughout the central nervous system, and have profound effects on neuroendocrine function. In man, exogenous opiates and opioids elevate circulating prolactin, GH and TSH, and suppress the release of the gonadotrophins and pro-opiocortin-related peptides. However, unlike in other species, there is substantial evidence for a physiological role of endogenous opioids only in the case of the gonadotrophins and ACTH/LPH. Most evidence suggests that LH and FSH are modula...

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Authors: Grossman, A

• Publication status: Published
• Journal: Clinics in endocrinology and metabolism
• Volume: 12
• Issue: 3
• Pages: 725-746
• Publication date: 1983-11-01
• ISSN: 0300-595X
• Language: English
• Keywords: Follicle Stimulating Hormone; Female; Humans; Growth Hormone; Adrenocorticotropic Hormone; Receptors, Opioid; Brain; Morphine; Luteinizing Hormone; Male; Animals; Prolactin; Enkephalins; Thyrotropin; Hypothalamo-Hypophyseal System; Rats; Pituitary Gland, Posterior; Endorphins