- Abstract:
-
A randomized, open-label comparison of artesunate and quinine was conducted in 113 adults with clinically severe falciparum malaria in western Thailand. Mortality was 12% with artesunate and 22% with quinine treatment (relative risk, 0.53; 95% confidence interval, 0.23-1.26; P=.22). Multiple logistic regression analysis found admission plasma lactate level, Glasgow Coma Scale score, and total serum bilirubin level to be independent risk factors for death. Coma recovery and times to normalize ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1086/375059
-
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- Journal:
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
- Volume:
- 37
- Issue:
- 1
- Pages:
- 7-16
- Publication date:
- 2003-07-05
- DOI:
- EISSN:
-
1537-6591
- ISSN:
-
1058-4838
- URN:
-
uuid:ec3d940c-e08c-4772-8ecf-8437865fcd07
- Source identifiers:
-
15910
- Local pid:
- pubs:15910
- Language:
- English
- Keywords:
- Copyright date:
- 2003
Journal article
Randomized comparison of artesunate and quinine in the treatment of severe falciparum malaria.
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