Medulloblastoma of the cerebellar vermis with subarachnoid dissemination

Journal article

Medulloblastoma, the most frequent pediatric brain tumor, has a known propensity for subarachnoid dissemination. Spinal metastases indicate a poor prognosis. Intraventricular spread is much less common. We report a case of primary intraventricular dissemination with precocious puberty as the first clinical symptom due to a metastasis at the infundibulary stalk. This has not been reported so far as initial symptom of a medulloblastoma. Furthermore, we encountered an unusually mild contrast enhancement of the spinal and intraventricular metastases. Delayed scanning after contrast administration and FLAIR sequences proved to be particularly valuable in this case.

Authors: Krapf, H; Bühring, U; Friese, S; Küker, W

• Journal: Klinische Neuroradiologie
• Volume: 10
• Issue: 2
• Pages: 85-90
• Publication date: 2000-01-01
• DOI: 10.1007/s000620050006
• ISSN: 0939-7116
• Language: German
• Keywords: Medulloblastoma; MRI; Subarachnoid metastases; Contrast enhancement; Precocious puberty