The investigation of non-covalent interactions of amyloidogenic human lysozyme variants and camelid antibodies was discussed. The two naturally occuring human lysozyme variants were implicated in hereditary systemic amyloidosis. Tri-NAG was shown to bind to both free and associated lysozyme, implying that the enzyme was still active when bound to the antibody. The single-domain camelid antibody appears to bind with its antigen lysozyme and the variants thereof with a 1:1 stoichiometry. Amyloi...