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Journal article

Cell mediated rejection.

Abstract:

Rejection is the major barrier to successful transplantation and usually results from the integration of multiple mechanisms. Activation of elements of the innate immune system, triggered as a consequence of tissue injury sustained during cell isolation or organ retrieval as well as ischemia-reperfusion, will initiate and amplify the adaptive response. For cell mediated rejection, T cells require multiple signals for activation, the minimum being two signals; antigen recognition and costimula...

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Publisher copy:
10.1007/978-1-62703-493-7_3

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Journal:
Methods in molecular biology (Clifton, N.J.)
Volume:
1034
Pages:
71-83
Publication date:
2013
DOI:
EISSN:
1940-6029
ISSN:
1064-3745
URN:
uuid:ec2b3845-73fd-4d6f-b8ef-71ba9e9e148a
Source identifiers:
407532
Local pid:
pubs:407532

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