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Prostaglandin E1 increases in vivo and in vitro calcitriol biosynthesis in rabbits.

Abstract:

INTRODUCTION: Prostaglandins have an anabolic effect on bone. Possible mediation of this effect is via calcitriol. This study determines in vivo and in vitro effects of PGE(1) on calcitriol synthesis. METHODOLOGY: In vivo: rabbits received intravenous vehicle or prostaglandin E(1) (50 microg/day) for 20 days before measurements of serum total and ionic calcium, magnesium and phosphorus levels, total and bone-specific alkaline phosphatases, 25(OH)D(3), calcitriol, parathyroid hormone and calci...

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Publication status:
Published

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Publisher copy:
10.1016/j.plefa.2006.03.011

Authors


Velásquez-Forero, F More by this author
García, P More by this author
Triffitt, JT More by this author
Journal:
Prostaglandins, leukotrienes, and essential fatty acids
Volume:
75
Issue:
2
Pages:
107-115
Publication date:
2006-08-05
DOI:
EISSN:
1532-2823
ISSN:
0952-3278
URN:
uuid:ec28d2dd-f97a-42a5-9eee-be924b7e3489
Source identifiers:
108448
Local pid:
pubs:108448

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