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Journal article

Pointed and Tramtrack69 establish an EGFR-dependent transcriptional switch to regulate mitosis.

Abstract:

Cell division in animals must be regulated; during development, for example, proliferation often occurs in spatially and temporally restricted patterns, and loss of mitotic control underlies cancer. The epidermal growth factor receptor (EGFR) has been implicated extensively in the control of cell proliferation in metazoans; in addition, hyperactivity of the EGFR and its three relatives, ErbB2-ErbB4, are implicated in many cancers. But little is known about how these receptor tyrosine kinases ...

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Publication status:
Published

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Publisher copy:
10.1038/ncb887

Authors


Murawsky, CM More by this author
Travers, AA More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Nature cell biology
Volume:
4
Issue:
12
Pages:
976-980
Publication date:
2002-12-05
DOI:
EISSN:
1476-4679
ISSN:
1465-7392
URN:
uuid:ebf6dba3-1e26-4764-843c-f8ed0afb8fc6
Source identifiers:
356081
Local pid:
pubs:356081

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