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Fractionating spatial memory with glutamate receptor subunit-knockout mice.

Abstract:

In recent years, the contribution that different glutamate receptor subtypes and subunits make to spatial learning and memory has been studied extensively using genetically modified mice in which key proteins are knocked out. This has revealed dissociations between different aspects of spatial memory that were not previously apparent from lesion studies. For example, studies with GluA1 AMPAR [AMPA (alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid) receptor] subunit-knockout mice have ...

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Publication status:
Published

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Publisher copy:
10.1042/bst0371323

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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Journal:
Biochemical Society transactions
Volume:
37
Issue:
Pt 6
Pages:
1323-1327
Publication date:
2009-12-05
DOI:
EISSN:
1470-8752
ISSN:
0300-5127
URN:
uuid:ebe85682-df59-4bfe-bac8-fb9c993484df
Source identifiers:
2357
Local pid:
pubs:2357

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