Journal article
A functional proteomic method for the enrichment of peripheral membrane proteins reveals the collagen binding protein Hsp47 is exposed on the surface of activated human platelets.
- Abstract:
-
Platelets are small blood cells vital for hemostasis. Following vascular damage, platelets adhere to collagens and activate, forming a thrombus that plugs the wound and prevents blood loss. Stimulation of the platelet collagen receptor glycoprotein VI (GPVI) allows recruitment of proteins to receptor-proximal signaling complexes on the inner-leaflet of the plasma membrane. These proteins are often present at low concentrations; therefore, signaling-complex characterization using mass spectrom...
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- Publication status:
- Published
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- Publisher copy:
- 10.1021/pr900027j
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Authors
Bibliographic Details
- Journal:
- Journal of proteome research
- Volume:
- 8
- Issue:
- 6
- Pages:
- 2903-2914
- Publication date:
- 2009-06-01
- DOI:
- EISSN:
-
1535-3907
- ISSN:
-
1535-3893
- Source identifiers:
-
244374
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:244374
- UUID:
-
uuid:ebe0d553-d1e9-4f81-bbda-a42aa100593a
- Local pid:
- pubs:244374
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2009
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