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An analysis of the gene complement of a marsupial, Monodelphis domestica: evolution of lineage-specific genes and giant chromosomes.

Abstract:

The newly sequenced genome of Monodelphis domestica not only provides the out-group necessary to better understand our own eutherian lineage, but it enables insights into the innovative biology of metatherians. Here, we compare Monodelphis with Homo sequences from alignments of single nucleotides, genes, and whole chromosomes. Using PhyOP, we have established orthologs in Homo for 82% (15,250) of Monodelphis gene predictions. Those with single orthologs in each species exhibited a high median...

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Publication status:
Published

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Publisher copy:
10.1101/gr.6093907

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
Journal:
Genome research
Volume:
17
Issue:
7
Pages:
969-981
Publication date:
2007-07-05
DOI:
EISSN:
1549-5469
ISSN:
1088-9051
URN:
uuid:ebd8d6a7-9b71-4984-924e-ddf53ab31864
Source identifiers:
237825
Local pid:
pubs:237825

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