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The plasma concentration of the B cell activating factor is increased in children with acute malaria

Abstract:

Malaria-specific antibody responses in children often appear to be short-lived but the mechanisms underlying this phenomenon are not well understood. In this study, we investigated the relationship between the B-cell activating factor (BAFF) and its receptors expressed on B cells with antibody responses during and after acute malaria in children. Our results demonstrate that BAFF plasma levels increased during acute malarial disease and reflected disease severity. The expression profiles for ...

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Publisher copy:
10.1093/infdis/jir438

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Journal:
Journal of Infectious Diseases
Volume:
204
Issue:
6
Pages:
962-970
Publication date:
2011-09-15
DOI:
ISSN:
0022-1899
URN:
uuid:ebc6434d-c0c5-404f-b374-87d01b996028
Source identifiers:
179623
Local pid:
pubs:179623
Language:
English

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