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Journal article

Effect of cotrimoxazole on causes of death, hospital admissions and antibiotic use in HIV-infected children.

Abstract:

BACKGROUND: Cotrimoxazole prophylaxis reduces morbidity and mortality in HIV-1-infected children, but mechanisms for these benefits are unclear. METHODS: CHAP was a randomized trial comparing cotrimoxazole prophylaxis with placebo in HIV-infected children in Zambia where background bacterial resistance to cotrimoxazole is high. We compared causes of mortality and hospital admissions, and antibiotic use between randomized groups. RESULTS: Of 534 children (median age, 4.4 years; 32% 1-2 years),...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
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Journal:
AIDS (London, England)
Volume:
21
Issue:
1
Pages:
77-84
Publication date:
2007-01-05
DOI:
EISSN:
1473-5571
ISSN:
0269-9370
URN:
uuid:ebb663db-e5e5-411c-93d3-d244d7472ab8
Source identifiers:
423035
Local pid:
pubs:423035

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