Altered dorsal premotor-motor interhemispheric pathway activity in focal arm dystonia.

Journal article

Given the possible role of dorsal premotor cortex (PMd) in the pathophysiology of dystonia, we used transcranial magnetic stimulation (TMS) methods to study PMd and PMd-primary motor cortex (M1) interactions in patients with focal arm dystonia. Here, we tested the connectivity between left PMd and right M1 as well as the intracortical excitability of PMd in 11 right-handed patients with focal arm/hand dystonia and nine age-matched healthy controls. The results showed that excitability of the ...

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Authors: Koch, G; Schneider, S; Bäumer, T; Franca, M; Münchau, A

• Journal: Movement disorders : official journal of the Movement Disorder Society
• Volume: 23
• Issue: 5
• Pages: 660-668
• Publication date: 2008-04-01
• DOI: 10.1002/mds.21881
• EISSN: 1531-8257
• ISSN: 0885-3185
• Language: English
• Keywords: Dystonic Disorders; Frontal Lobe; Arm; Adult; Middle Aged; Male; Aged, 80 and over; Evoked Potentials, Motor; Neural Pathways; Neural Inhibition; Motor Cortex; Aged; Transcranial Magnetic Stimulation; Electrodiagnosis; Female; Humans