Journal article icon

Journal article

Minimum sample size for external validation of a clinical prediction model with a binary outcome

Abstract:

In prediction model research, external validation is needed to examine an existing model's performance using data independent to that for model development. Current external validation studies often suffer from small sample sizes and consequently imprecise predictive performance estimates. To address this, we propose how to determine the minimum sample size needed for a new external validation study of a prediction model for a binary outcome. Our calculations aim to precisely estimate calibra...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1002/sim.9025

Authors


More by this author
Role:
Author
ORCID:
0000-0001-8699-0735
More by this author
Role:
Author
ORCID:
0000-0002-1790-2719
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author
ORCID:
0000-0002-2772-2316
More by this author
Role:
Author
ORCID:
0000-0003-2504-2613
More by this author
Role:
Author
ORCID:
0000-0001-7481-0282
Publisher:
Wiley
Journal:
Statistics in Medicine More from this journal
Volume:
40
Issue:
19
Pages:
4230-4251
Place of publication:
England
Publication date:
2021-05-24
Acceptance date:
2021-03-22
DOI:
EISSN:
1097-0258
ISSN:
0277-6715
Pmid:
34031906
Language:
English
Keywords:
Pubs id:
1179487
Local pid:
pubs:1179487
Deposit date:
2022-08-14

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP