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Screening for prolonged incubation of HTLV-I infection in British and Jamaican relatives of British patients with tropical spastic paraparesis.

Abstract:

OBJECTIVE: To compare the prevalence of antibody to and proviral DNA of the retrovirus HTLV-I in relatives of 11 British patients with tropical spastic paraparesis who had migrated from Jamaica before they developed symptoms, and to examine factors possibly related to transmission of HTLV-I. DESIGN: Migrant, family study. Antibody state was determined by several methods and confirmed by western blotting; the polymerase chain reaction was used to detect proviral DNA. SETTING: Britain and Jamai...

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Publication status:
Published

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Publisher copy:
10.1136/bmj.300.6720.300

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division, Biomedical Research Centre
Role:
Author
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Journal:
BMJ (Clinical research ed.)
Volume:
300
Issue:
6720
Pages:
300-304
Publication date:
1990-02-05
DOI:
EISSN:
1756-1833
ISSN:
0959-8138
URN:
uuid:eb8bf162-1e12-4d3c-a3c7-6268c2132502
Source identifiers:
26958
Local pid:
pubs:26958

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