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Matched unrelated donor bone marrow transplantation for chronic myeloid leukaemia in chronic phase: comparison of ex vivo and in vivo T-cell depletion.

Abstract:

Between January 1985 and March 1992, 48 patients with chronic phase CML underwent BMT from volunteer unrelated donors (MUD) serologically identical at HLA-A, B and DR loci. 19 patients received donor marrow ex vivo T-cell depleted (EX-TCD) with Campath monoclonal antibodies. 29 patients received unmanipulated donor marrow with CsA/MTX GVHD prophylaxis; 28 received additional intravenous antilymphocyte therapy from day +1 to +5 (IN-TCD). Overall 26 patients survive at median follow up of 362 d...

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Publication status:
Published

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Authors


Cullis, JO More by this author
Szydlo, RM More by this author
Schwarer, AP More by this author
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Volume:
11 Suppl 1
Pages:
107-111
Publication date:
1993
EISSN:
1476-5365
ISSN:
0268-3369
URN:
uuid:eb88b41c-4cb5-4f1b-b813-b17b475d4756
Source identifiers:
25810
Local pid:
pubs:25810

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