- Abstract:
-
The development of effective new treatments is greatly facilitated by the understanding of the mechanisms of disease. In rheumatoid arthritis, there has been progress in understanding its immunology, the HLA class II predisposition including the 'shared epitope' and more recently in understanding the importance of proinflammatory cytokines. Here we review our work in defining TNFα as a therapeutic target in rheumatoid arthritis, from an understanding of molecular pathogenesis in vitro, to for...
Expand abstract - Publisher copy:
- 10.1016/S1297-319X(01)00335-9
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- Journal:
- Joint Bone Spine
- Volume:
- 69
- Issue:
- 1
- Pages:
- 12-18
- Publication date:
- 2002
- DOI:
- ISSN:
-
1297-319X
- URN:
-
uuid:eb75327b-6970-4202-b176-8e6acc632ec5
- Source identifiers:
-
226196
- Local pid:
- pubs:226196
- Language:
- English
- Keywords:
- Copyright date:
- 2002
Journal article
Discovery of TNF-α as a therapeutic target in rheumatoid arthritis: Preclinical and clinical studies
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