Journal article
Discovery of TNF-α as a therapeutic target in rheumatoid arthritis: Preclinical and clinical studies
- Abstract:
-
The development of effective new treatments is greatly facilitated by the understanding of the mechanisms of disease. In rheumatoid arthritis, there has been progress in understanding its immunology, the HLA class II predisposition including the 'shared epitope' and more recently in understanding the importance of proinflammatory cytokines. Here we review our work in defining TNFα as a therapeutic target in rheumatoid arthritis, from an understanding of molecular pathogenesis in vitro, to for...
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- Publisher copy:
- 10.1016/S1297-319X(01)00335-9
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Bibliographic Details
- Journal:
- Joint Bone Spine
- Volume:
- 69
- Issue:
- 1
- Pages:
- 12-18
- Publication date:
- 2002-01-01
- DOI:
- ISSN:
-
1297-319X
- Source identifiers:
-
226196
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:226196
- UUID:
-
uuid:eb75327b-6970-4202-b176-8e6acc632ec5
- Local pid:
- pubs:226196
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2002
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