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Fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): Application to 6-[18F]fluoro-l-DOPA

Abstract:
The Ag-mediated electrophilic [18F]fluorination of an arylboronic ester is reported. This new radiochemical transformation uses [ 18F]selectfluor bis(triflate) in acetone. The process gave 6-[ 18F]fluoro-l-DOPA with a RCY of 19 ± 12% and a specific activity of 2.6 ± 0.3 GBq μmol-1. © 2013 The Royal Society of Chemistry.

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Publisher copy:
10.1039/c2cc38646a

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Journal:
Chemical Communications More from this journal
Volume:
49
Issue:
14
Pages:
1386-1388
Publication date:
2013-02-18
DOI:
EISSN:
1364-548X
ISSN:
1359-7345


Language:
English
Pubs id:
pubs:379431
UUID:
uuid:eb741aec-76bd-4eaf-b72d-1e4a0a35f949
Local pid:
pubs:379431
Source identifiers:
379431
Deposit date:
2013-11-16

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