Journal article icon

Journal article

Proteoglycans in health and disease: the multiple roles of syndecan shedding.

Abstract:

Proteolytic processes in the extracellular matrix are a major influence on cell adhesion, migration, survival, differentiation and proliferation. The syndecan cell-surface proteoglycans are important mediators of cell spreading on extracellular matrix and respond to growth factors and other biologically active polypeptides. The ectodomain of each syndecan is constitutively shed from many cultured cells, but is accelerated in response to wound healing and diverse pathophysiological events. Ect...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Journal:
FEBS J
Volume:
277
Issue:
19
Pages:
3876-3889
Publication date:
2010-08-31
DOI:
EISSN:
1742-4658
ISSN:
1742-464X
URN:
uuid:eb741434-81dc-43a6-80fe-bbacd38d8a33
Source identifiers:
224402
Local pid:
pubs:224402

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP