A putatively phase variable gene (dca) required for natural competence in Neisseria gonorrhoeae but not Neisseria meningitidis is located within the division cell wall (dcw) gene cluster.

Journal article

A cluster of 18 open reading frames (ORFs), 15 of which are homologous to genes involved in division and cell wall synthesis, has been identified in Neisseria gonorrhoeae and Neisseria meningitidis. The three additional ORFs, internal to the dcw cluster, are not homologous to dcw-related genes present in other bacterial species. Analysis of the N. meningitidis strain MC58 genome for foreign DNA suggests that these additional ORFs have not been acquired by recent horizontal exchange, indicatin...

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Authors: Snyder, L; Saunders, N; Shafer, WM

• Publication status: Published
• Journal: Journal of bacteriology
• Volume: 183
• Issue: 4
• Pages: 1233-1241
• Publication date: 2001-02-01
• DOI: 10.1128/jb.183.4.1233-1241.2001
• EISSN: 1098-5530
• ISSN: 0021-9193
• Language: English
• Keywords: Species Specificity; Gene Transfer, Horizontal; Open Reading Frames; Bacterial Proteins; Neisseria meningitidis; Neisseria gonorrhoeae; Transformation, Bacterial; Multigene Family; Amino Acid Sequence; Mutagenesis, Insertional; Sequence Homology, Amino Acid; Membrane Proteins; Molecular Sequence Data