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A putatively phase variable gene (dca) required for natural competence in Neisseria gonorrhoeae but not Neisseria meningitidis is located within the division cell wall (dcw) gene cluster.

Abstract:

A cluster of 18 open reading frames (ORFs), 15 of which are homologous to genes involved in division and cell wall synthesis, has been identified in Neisseria gonorrhoeae and Neisseria meningitidis. The three additional ORFs, internal to the dcw cluster, are not homologous to dcw-related genes present in other bacterial species. Analysis of the N. meningitidis strain MC58 genome for foreign DNA suggests that these additional ORFs have not been acquired by recent horizontal exchange, indicatin...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Journal of bacteriology
Volume:
183
Issue:
4
Pages:
1233-1241
Publication date:
2001-02-05
DOI:
EISSN:
1098-5530
ISSN:
0021-9193
URN:
uuid:eb73c35e-bc7b-46b6-9fdd-6379a87de874
Source identifiers:
26612
Local pid:
pubs:26612

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