Journal article
Active nematics with deformable particles
- Abstract:
- The hydrodynamic theory of active nematics has been often used to describe the spatio-temporal dynamics of cell flows and motile topological defects within soft confluent tissues. Those theories, however, often rely on the assumption that tissues consist of cells with a fixed, anisotropic shape and do not resolve dynamical cell shape changes due to flow gradients. In this paper we extend the continuum theory of active nematics to include cell shape deformability. We find that circular cells in tissues must generate sufficient active stress to overcome an elastic barrier to deforming their shape in order to drive tissue-scale flows. Above this threshold the systems enter a dynamical steady-state with regions of elongated cells and strong flows coexisting with quiescent regions of isotropic cells.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 3.2MB, Terms of use)
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- Publisher copy:
- 10.1039/d3sm00627a
Authors
- Publisher:
- Royal Society of Chemistry
- Journal:
- Soft Matter More from this journal
- Volume:
- 19
- Issue:
- 35
- Pages:
- 6664-6670
- Publication date:
- 2023-08-14
- Acceptance date:
- 2023-08-12
- DOI:
- EISSN:
-
1744-6848
- ISSN:
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1744-683X
- Pmid:
-
37609906
- Language:
-
English
- Keywords:
- Pubs id:
-
1518437
- Local pid:
-
pubs:1518437
- Deposit date:
-
2023-09-02
Terms of use
- Copyright holder:
- Royal Society of Chemistry
- Copyright date:
- 2023
- Rights statement:
- © The Royal Society of Chemistry 2023. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
- Licence:
- Other
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