In vitro activity of sanfetrinem (GV104326), a new trinem antimicrobial agent, versus Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis.

Journal article

Sanfetrinem, formerly GV104326, is a new trinem antimicrobial agent with extensive in vitro activity for a variety of different bacteria. The activity of sanfetrinem was determined using a broth microdilution MIC method versus a large number of clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis obtained in a recent 30-center United States surveillance study. The sanfetrinem MIC50 and MIC90 values for these three organism groups were 0.015 and 0.5 microgram/ml, 0.25, and 0.5 microgram/ml, and 0.015 and 0.03, respectively.

Authors: Doern, G; Pierce, G; Brueggemann, A

• Journal: Diagnostic microbiology and infectious disease
• Volume: 26
• Issue: 1
• Pages: 39-42
• Publication date: 1996-09-01
• DOI: 10.1016/s0732-8893(96)00173-3
• EISSN: 1879-0070
• ISSN: 0732-8893
• Language: English
• Keywords: Haemophilus influenzae; Microbial Sensitivity Tests; Streptococcus pneumoniae; Lactams; Anti-Bacterial Agents; Moraxella (Branhamella) catarrhalis