Journal article
Reduction in precursors of cytotoxic T lymphocytes and of cells with natural killer-like activity in spleens of cyclophosphamide-treated mice.
- Abstract:
-
The effect of cyclophosphamide (CY) on precursors of cytotoxic T lymphocytes (CTL), specific for Moloney-murine leukemia virus (M-MuL V)- induced antigens, and on the precursors of cells having natural killer (NK)-like activity was studied by means of limiting dilution assay. Pre-treatment with a single CY dose of 100 mg/kg induced a marked reduction not only in the total spleen cell number but also in the frequencies of M-MuL V-specific CTL, and NK-like cell precursors. Maximal effect was ob...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/0192-0561(84)90092-4
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Authors
Bibliographic Details
- Journal:
- International journal of immunopharmacology
- Volume:
- 6
- Issue:
- 5
- Pages:
- 529-534
- Publication date:
- 1984-01-01
- DOI:
- ISSN:
-
0192-0561
- URN:
-
uuid:eb557ccb-45de-4c64-97e6-42455aa846db
- Source identifiers:
-
35473
- Local pid:
- pubs:35473
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright date:
- 1984
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