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Depletion effects and loop formation in self-avoiding polymers.

Abstract:
Langevin dynamics is employed to study the looping kinetics of self-avoiding polymers both in ideal and crowded solutions. A rich kinetics results from the competition of two crowding-induced effects: the depletion attraction and the enhanced viscous friction. For short chains, the enhanced friction slows down looping, while for longer chains, the depletion attraction renders it more frequent and persistent. We discuss the possible relevance of the findings for chromatin looping in living cells.
Publication status:
Published

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Authors


Marenduzzo, D More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Micheletti, C More by this author
Journal:
Physical review letters
Volume:
97
Issue:
17
Pages:
178302
Publication date:
2006-10-05
DOI:
EISSN:
1079-7114
ISSN:
0031-9007
URN:
uuid:eb3b0e45-39d3-4baa-829b-d8231272fddf
Source identifiers:
16283
Local pid:
pubs:16283

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