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Journal article

Regulation of fibroblast migration by tenascin-C.

Abstract:

Synthesis of new tissue by fibroblasts is required for tissue rebuilding in response to injury. Fibroblast migration from surrounding healthy tissue into the fibrin-fibronectin provisional matrix deposited upon injury is a key rate-limiting step of this stage of tissue repair. These events must be tightly regulated. Excessive deposition of scar tissue is the major hallmark of fibrotic disease. Tenascin-C is an extracellular matrix glycoprotein that is transiently expressed upon tissue injury,...

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Publication status:
Published

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Publisher copy:
10.1042/bst0350695

Authors


Journal:
Biochemical Society transactions
Volume:
35
Issue:
Pt 4
Pages:
695-697
Publication date:
2007-08-05
DOI:
EISSN:
1470-8752
ISSN:
0300-5127
URN:
uuid:eb2ca429-e533-4240-bc61-9ec4904680ae
Source identifiers:
225484
Local pid:
pubs:225484

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