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Journal article

Oral artesunate dose-response relationship in acute falciparum malaria.

Abstract:

The combination of an oral artemisinin derivative (usually artesunate) and mefloquine has become standard treatment for multidrug-resistant falciparum malaria in several parts of Southeast Asia. The doses of artesunate used in monotherapy and combination treatment have largely been derived empirically. In order to characterize the in vivo dose-response relationship for artesunate and thus rationalize dosing, 47 adult patients with acute uncomplicated falciparum malaria and parasitemia > or...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Thaiaporn, I More by this author
Chanthapadith, K More by this author
Suputtamongkol, Y More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Journal:
Antimicrobial agents and chemotherapy
Volume:
46
Issue:
3
Pages:
778-782
Publication date:
2002-03-05
DOI:
EISSN:
1098-6596
ISSN:
0066-4804
URN:
uuid:eb0e9f10-25b4-4d0f-8fd7-00655c4eb716
Source identifiers:
38086
Local pid:
pubs:38086

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