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Prevalence of radiographic hip osteoarthritis is increased in high bone mass

Abstract:

Objective: Epidemiological studies have shown an association between increased bone mineral density (BMD) and osteoarthritis (OA), but whether this represents cause or effect remains unclear. In this study, we used a novel approach to investigate this question, determining whether individuals with High Bone Mass (HBM) have a higher prevalence of radiographic hip OA compared with controls. Design: HBM cases came from the UK-based HBM study: HBM was defined by BMD Z-score. Unaffected relatives ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.joca.2014.06.007

Authors


Hardcastle, SA More by this author
Gregson, CL More by this author
Thomas, GER More by this author
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Arthritis Research UK More from this funder
Oxford NIHR Musculoskeletal Biomedical Research Unit More from this funder
Wellcome Trust More from this funder
Publisher:
W.B. Saunders Ltd Publisher's website
Journal:
Osteoarthritis and Cartilage Journal website
Volume:
22
Issue:
8
Pages:
1120-1128
Publication date:
2014-08-05
DOI:
EISSN:
1522-9653
ISSN:
1063-4584
URN:
uuid:eae712dc-3036-4d58-8b79-a37f05c47ebf
Source identifiers:
480847
Local pid:
pubs:480847
Language:
English
Keywords:

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