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Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal-Retzius cells from the cortical hem.

Abstract:

Cajal-Retzius (CR) cells play a crucial role in the formation of the cerebral cortex, yet the molecules that control their development are largely unknown. Here, we show that Ebf transcription factors are expressed in forebrain signalling centres-the septum, cortical hem and the pallial-subpallial boundary-known to generate CR cells. We identified Ebf2, through fate mapping studies, as a novel marker for cortical hem- and septum-derived CR cells. Loss of Ebf2 in vivo causes a transient decrea...

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Publication status:
Published

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Publisher copy:
10.1016/j.ydbio.2012.02.034

Authors


Badaloni, A More by this author
Cariboni, A More by this author
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Journal:
Developmental biology
Volume:
365
Issue:
1
Pages:
277-289
Publication date:
2012-05-05
DOI:
EISSN:
1095-564X
ISSN:
0012-1606
URN:
uuid:eae2602b-04bd-4551-8609-e584ae101cc2
Source identifiers:
316249
Local pid:
pubs:316249

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