Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal-Retzius cells from the cortical hem.

Journal article

Cajal-Retzius (CR) cells play a crucial role in the formation of the cerebral cortex, yet the molecules that control their development are largely unknown. Here, we show that Ebf transcription factors are expressed in forebrain signalling centres-the septum, cortical hem and the pallial-subpallial boundary-known to generate CR cells. We identified Ebf2, through fate mapping studies, as a novel marker for cortical hem- and septum-derived CR cells. Loss of Ebf2 in vivo causes a transient decrea...

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Authors: Chiara, F; Badaloni, A; Croci, L; Yeh, M; Cariboni, A

• Publication status: Published
• Journal: Developmental biology
• Volume: 365
• Issue: 1
• Pages: 277-289
• Publication date: 2012-05-01
• DOI: 10.1016/j.ydbio.2012.02.034
• EISSN: 1095-564X
• ISSN: 0012-1606
• Language: English
• Keywords: Basic Helix-Loop-Helix Transcription Factors; Cell Movement; Neurons; Cerebral Cortex; Transcription Factors; Cell Lineage; Mice; Animals; Cell Differentiation